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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC5
All Species:
40.3
Human Site:
Y225
Identified Species:
73.89
UniProt:
Q13769
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13769
NP_001002877.1
683
78508
Y225
E
I
E
V
K
K
E
Y
L
S
S
L
Q
P
R
Chimpanzee
Pan troglodytes
XP_515059
683
78517
Y225
E
I
E
V
K
K
E
Y
L
S
S
L
Q
P
R
Rhesus Macaque
Macaca mulatta
XP_001106294
689
79038
Y225
E
I
E
V
K
K
E
Y
L
S
S
L
Q
P
R
Dog
Lupus familis
XP_534728
683
78595
Y225
E
I
E
V
K
K
E
Y
L
S
S
L
Q
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKT7
683
78667
Y225
E
I
E
V
K
R
D
Y
L
S
S
L
Q
P
R
Rat
Rattus norvegicus
Q68FX7
682
78642
Y225
E
I
E
V
K
K
E
Y
L
S
S
L
Q
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517072
363
40527
Chicken
Gallus gallus
Q5ZJK1
698
80563
Y224
E
I
E
V
K
K
E
Y
L
S
S
L
Q
P
R
Frog
Xenopus laevis
Q7ZXA8
678
77744
Y220
E
I
E
I
K
K
E
Y
L
N
T
L
Q
P
Q
Zebra Danio
Brachydanio rerio
Q6NY52
684
77815
Y225
A
I
E
Q
K
R
E
Y
L
S
S
L
Q
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1F4
616
70871
A175
R
Y
V
S
F
A
P
A
L
R
T
L
Q
S
A
Honey Bee
Apis mellifera
XP_396039
657
75378
S216
E
N
K
K
A
V
A
S
S
I
A
L
K
Q
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798236
699
79519
Y232
S
I
H
Q
K
K
D
Y
L
E
S
L
Q
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
95.5
98
N.A.
96.1
96.1
N.A.
45.2
83.2
76.5
68.4
N.A.
25.7
37
N.A.
46.2
Protein Similarity:
100
100
96.3
99.1
N.A.
97.9
98.3
N.A.
49.7
90.9
87.1
83
N.A.
45.3
56.2
N.A.
65.2
P-Site Identity:
100
100
100
100
N.A.
86.6
100
N.A.
0
100
73.3
73.3
N.A.
20
13.3
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
100
100
80
N.A.
26.6
33.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
8
8
8
0
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% D
% Glu:
70
0
70
0
0
0
62
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
77
0
8
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
8
8
77
62
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
85
0
0
93
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
77
0
% P
% Gln:
0
0
0
16
0
0
0
0
0
0
0
0
85
8
8
% Q
% Arg:
8
0
0
0
0
16
0
0
0
8
0
0
0
0
62
% R
% Ser:
8
0
0
8
0
0
0
8
8
62
70
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
8
% T
% Val:
0
0
8
54
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _